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HealthDr. Hisamitsu Hayashi, a researcher behind a new therapy for Progressive Familial Intrahepatic Cholestasis (PFIC), discusses a treatment targeting the bile salt export pump (BSEP). Current US-approved PFIC drugs mainly address pruritus, but this therapy focuses on the underlying disease mechanism. Dr. Hayashi shares insights on diagnosis, clinical data, and future developments in PFIC treatment.
HCPLive·
EntertainmentThe Supreme Court told actor Rajpal Yadav to make a good movie and entertain people again to rebuild his image. The court noted Yadav paid ₹1.15 crore in cheque-bounce cases and was informed about a prospective buyer willing to pay ₹85 lakh by October 12. Yadav admitted financial losses of ₹200-250 crore over 13 years, including ₹17 crore lost on the film Ata Pata Laapata.
Hindustan Times··New Delhi
SportsAjit Agarkar, a prominent figure in Indian cricket history, served as chief selector and received both praise for good selections and criticism for player rejections. During his tenure, the Indian team won three ICC trophies. However, discussions often focused more on the retirements of Virat Kohli, Rohit Sharma, and Ravichandran Ashwin than on Agarkar's contributions.
News18Hi Sports·
ScienceMahesh Kakde, a professor at the Indian Institute of Science (IISc) Bengaluru, has been awarded the Ramanujan Prize 2026. The International Centre for Theoretical Physics (ICTP) and the International Mathematical Union (IMU) honored him for his significant contributions to algebraic number theory.
Hindustan Times··Bengaluru
PoliticsFormer Singapore diplomat Bilahari Kausikan criticized Pakistan's military under Army chief Field Marshal Asim Munir, questioning its ideological shift and Pakistan's purpose after Bangladesh's 1971 independence. He said Pakistan was originally a homeland for South Asian Muslims, but that rationale ended with Bangladesh's split. Kausikan described the military as the country's precarious glue, shifting from a secular to a religious force.
News18 World·
EntertainmentThe release date of the film 'Kaali Kheti' starring Jackie Shroff, Sharad Kelkar, and Neha Sargam has been postponed from October 23 to November 20, 2026. The makers delayed the release to avoid clashing with several other major films releasing in October, including Ajay Devgn's 'Drishyam 3' and Ayushmann Khurrana's 'Udata Teer'.
Amar Entertainment·
HCPLive·
Dr. Hisamitsu Hayashi, a researcher behind a new therapy for Progressive Familial Intrahepatic Cholestasis (PFIC), discusses a treatment targeting the bile salt export pump (BSEP). Current US-approved PFIC drugs mainly address pruritus, but this therapy focuses on the underlying disease mechanism. Dr. Hayashi shares insights on diagnosis, clinical data, and future developments in PFIC treatment.
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